Elective Single Embryo Transfer Boosts The Chance Of A Healthy Baby

Link Women who undergo elective single embryo transfer as part of ... IVF are five times more likely to give birth to a healthy baby compared with double embryo transfer ...

The study recommends that clinicians should, from now on, advise women to have an elective single embryo transfer (eSET) as part of assisted reproduction treatment rather than a double embryo transfer (DET).

Although there has been increasing success in infertility treatments in recent years, there have also been growing concerns about rising rates of multiple pregnancies, which are associated with increased maternal and perinatal illness and death, as well as increased costs to the health service.

A previous review of studies comparing data on eSET versus DET concluded that, although eSET reduced the odds of multiple pregnancies, it halved the odds of live birth per fresh cycle of treatment.

However, there has been, until now, a lack of evidence about the effect of single versus double embryo transfer in different groups of women and on outcomes such as miscarriage, preterm birth and low birth weight.

So an international team of researchers, led by the University of Aberdeen, studied data on 1,367 women from eight eligible trials ...

... the chances of a full-term single birth ... following single embryo transfer were almost five times higher than those following double embryo transfer.

Single embryo transfer was also seen to reduce the risk of premature births ...

The chance of delivering a baby with low birth weight for single embryo transfer cases was a third of the chance for double embryo transfer cases.

In other words, the chance of a having a healthy baby (not premature or low birth weight) is higher with single embryo transfer than with double embryo transfer ...